Tocotrienols (bixa orellana) are part of the Vitamin E family. Tocotrienols were originally discovered by Pennock and Whittle in 1964. In the early 1980s, Tocotrienols were shown to lower cholesterol. Shortly thereafter, during the 1990s, Tocotrienols started being investigated for their anti-carcinogenic properties. Since then, Tocotrienols have been studied extensively in numerous clinical trials and are proven to reduce blood cholesterol levels by 5–35 percent.
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Kulkarni, S., S. P. Ghosh, et al. "Gamma-tocotrienol protects hematopoietic stem and progenitor cells in mice after total-body irradiation." Radiat Res 173(6): 738-47.
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